The molecular pathogenesis of colorectal cancer and its potential application to colorectal cancer screening william m grady md 2 3 and sanford d markowitz md phd 1 1 department of medicine case western reserve university cleveland oh. Molecular pathogenesis of colorectal cancer implications for molecular diagnosis christian n arnold md 1 ajay goel phd 2 hubert e blum md 1 c richard boland md 2 1 department of internal medicine university of freiburg freiburg germany 2 division of gastroenterology department of in. Owing to its high incidence and anatomical accessibility colorectal cancer has become the most extensively studied human neoplasm with respect to molecular pathogenesis. This book explores the past present and future of colorectal cancer genetics with particular emphasis on how knowledge of the molecular pathogenesis of the disease leads to the development of novel therapeutic strategies
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